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Ultimate Spider-Man (2024)

Ultimate Spider-Man #21

Francesco Manna Variant

Marvel · November 2025

Cover of Francesco Manna Variant

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About this issue

Writer
Jonathan Hickman
Artist
David Messina
Colorist
Erick Arciniega and Matthew Wilson
Letterer
Cory Petit
Cover
Alexander Lozano, Francesco Manna, Marco Checchetto, Matthew Wilson, and Mattia Iacono
Editor
Wil Moss
Assistant Editor
Michelle Marchese
Designer
Jay Bowen
Characters
Aunt May, Black Cat, Bullseye, Doctor Octopus, Gwen Stacy, Harry Osborn, J. Jonah Jameson, Kingpin, Mary Jane Watson, Mister Negative, Mole Man, Mysterio (Beck), Richard Parker (6160), Robbie Robertson, Spider-Girl (Parker), Spider-Man, Uncle Ben, Walter Hardy, and Wesley
Teams
Sinister Six
Cover date
November 2025
On sale
24 September 2025
Cover price
$4.99
UPC
75960620796102121
Pages
32
Rating
Teen

THE FINAL MEETING OF THE SINISTER SIX? Blood boils over as these warring villains gather to destroy each other once and for all... or will they reunite against their common enemy, Spider-Man?

Variants